DISEASES

Disease-gene associations mined from literature

Literature on NOS1AP

NOS1AP [ENSP00000355133]

Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein; Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity).

Synonyms:  NOS1AP,  NOS1APp,  hNOS1AP,  E9PIP8,  E9PSG0 ...

Linkouts:  STRING  Pharos  UniProt