Literature on THEM4
THEM4 [ENSP00000357804]
Acyl-coenzyme A thioesterase THEM4; Has acyl-CoA thioesterase activity towards medium and long- chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane. ECO:0000269|PubMed:19168129, ECO:0000269|PubMed:19421406,
Synonyms: THEM4, THEM4p, hTHEM4, E9PLJ7, F6XC58 ...