DISEASES

Disease-gene associations mined from literature

Literature on SLC2A2

SLC2A2 [ENSP00000323568]

Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose (PubMed:8027028, PubMed:16186102, PubMed:23396969, PubMed:28083649). Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell . May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney . Also able to mediate the transport of dehydroascorbate . ECO:0000269|PubMed:23396969, ECO:0000269|PubMed:28083649,; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.

Synonyms:  SLC2A2,  SLC2A2p,  hSLC2A2,  A0A0C4DH64,  C9J0E8 ...

Linkouts:  STRING  Pharos  UniProt  OMIM