DISEASES

Disease-gene associations mined from literature

Literature on BID

BID [ENSP00000318822]

BH3-interacting domain death agonist p11; The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.

Synonyms:  BID,  A8ASI8,  B2ZP78,  B2ZP79,  P55957 ...

Linkouts:  STRING  Pharos  UniProt  OMIM