DISEASES

Disease-gene associations mined from literature

Literature on TTC19

TTC19 [ENSP00000261647]

Tetratricopeptide repeat protein 19, mitochondrial; Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1 . Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation of UQCRFS1 into the complex III and whose presence is detrimental for its catalytic activity .

Synonyms:  TTC19,  TTC19p,  hTTC19,  A0A024RD83,  K7EJA1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM