DISEASES

Disease-gene associations mined from literature

Literature on SCN10A

SCN10A [ENSP00000390600]

Sodium channel protein type 10 subunit alpha; Tetrodotoxin-resistant channel that mediates the voltage- dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.

Synonyms:  SCN10A,  SCN10Ap,  hSCN10A,  A0A2R8Y6J6,  A0A2R8Y7H0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM