DISEASES

Disease-gene associations mined from literature

Literature on HNRNPL

HNRNPL [ENSP00000221419]

Heterogeneous nuclear ribonucleoprotein L; Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements (PubMed:11809897, PubMed:22570490, PubMed:24164894, PubMed:25623890, PubMed:26051023). Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts . Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter . ECO:0000269|PubMed:22570490, ECO:0000269|PubMed:25623890,

Synonyms:  HNRNPL,  A0A3B3ITJ4,  B4DVF8,  M0QXS5,  M0QYL7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM