Literature on CES3
CES3 [ENSP00000304782]
Carboxylesterase 3; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]- carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.
Synonyms: CES3, CES3p, hCES3, A0A0C4DFY7, H3BRE5 ...