Literature on CASP10
CASP10 [ENSP00000286186]
Caspase-10 subunit p23/17; Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive. ; Belongs to the peptidase C14A family.
Synonyms: CASP10, CASP10p, hCASP10, A0A0S2Z3G5, A0A0S2Z3Z5 ...