DISEASES

Disease-gene associations mined from literature

Literature on CDK20

CDK20 [ENSP00000322343]

Cyclin-dependent kinase 20; Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.

Synonyms:  CDK20,  CDK20p,  hCDK20,  A0A0S2Z5B6,  Q8IZL9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM