Literature on NCOR2
NCOR2 [ENSP00000384018]
Nuclear receptor corepressor 2; Transcriptional corepressor . Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 4 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation .
Synonyms: NCOR2, NCOR2p, hNCOR2, A0A384DVL6, C9J0Q5 ...