DISEASES

Disease-gene associations mined from literature

Literature on IL17RA

IL17RA [ENSP00000320936]

Interleukin-17 receptor A; Receptor for IL17A . Receptor for IL17F . Binds to IL17A with higher affinity than to IL17F . Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC . Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC . Receptor for IL17C as part of a heterodimeric complex with IL17RE . Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6 . ECO:0000269|PubMed:18684971, ECO:0000269|PubMed:19838198,

Synonyms:  IL17RA,  IL17RAp,  hIL17RA,  Q96F46,  Q96F46p ...

Linkouts:  STRING  Pharos  UniProt  OMIM