DISEASES

Disease-gene associations mined from literature

Literature on ZP3

ZP3 [ENSP00000378326]

Processed zona pellucida sperm-binding protein 3; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.

Synonyms:  ZP3,  ZP3p,  hZP3,  E9PFI9,  H0Y3M4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM