DISEASES

Disease-gene associations mined from literature

Literature on KIR3DL2

KIR3DL2 [ENSP00000325525]

Killer cell immunoglobulin-like receptor 3DL2; Receptor on natural killer (NK) cells and T cells for MHC class I molecules . Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions . Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity . ; Belongs to the immunoglobulin superfamily.

Synonyms:  KIR3DL2,  KIR3DL2p,  hKIR3DL2,  A0A0U1WNF3,  P43630 ...

Linkouts:  STRING  Pharos  UniProt  OMIM