DISEASES

Disease-gene associations mined from literature

Literature on PYCR3

PYCR3 [ENSP00000220966]

Pyrroline-5-carboxylate reductase 3; Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline.

Synonyms:  PYCR3,  PYCR3p,  hPYCR3,  A0A087WTU2,  A0A0A0MQS1 ...

Linkouts:  STRING  Pharos  UniProt