DISEASES

Disease-gene associations mined from literature

Literature on TNS2

TNS2 [ENSP00000319756]

Tensin-2; Tyrosine-protein phosphatase which regulates cell motility proliferation and muscle-response to insulin (PubMed:15817639, PubMed:23401856). In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its degradation and muscle atrophy . Negatively regulates PI3K-AKT pathway activation .

Synonyms:  TNS2,  TNS2p,  hTNS2,  A0A024RB48,  F8VV64 ...

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