Literature on TNS2
TNS2 [ENSP00000319756]
Tensin-2; Tyrosine-protein phosphatase which regulates cell motility proliferation and muscle-response to insulin (PubMed:15817639, PubMed:23401856). In muscles and under catabolic conditions, dephosphorylates IRS1 leading to its degradation and muscle atrophy . Negatively regulates PI3K-AKT pathway activation .
Synonyms: TNS2, TNS2p, hTNS2, A0A024RB48, F8VV64 ...