DISEASES

Disease-gene associations mined from literature

Literature on ZFC3H1

ZFC3H1 [ENSP00000368017]

Zinc finger C3H1 domain-containing protein; Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters.

Synonyms:  ZFC3H1,  ZFC3H1p,  hZFC3H1,  G3V1X1,  O60293 ...

Linkouts:  STRING  Pharos  UniProt