DISEASES

Disease-gene associations mined from literature

Literature on MTHFS

MTHFS [ENSP00000258874]

5-formyltetrahydrofolate cyclo-ligase; Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5- formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.

Synonyms:  MTHFS,  A0A0U1RQM3,  H3BMB9,  H3BN04,  P49914 ...

Linkouts:  STRING  Pharos  UniProt  OMIM