DISEASES

Disease-gene associations mined from literature

Literature on BRK1

BRK1 [ENSP00000432472]

Protein BRICK1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).

Synonyms:  BRK1,  BRK1p,  hBRK1,  Q8WUW1,  Q8WUW1p ...

Linkouts:  STRING  Pharos  UniProt