DISEASES

Disease-gene associations mined from literature

Literature on GPR39

GPR39 [ENSP00000327417]

G-protein coupled receptor 39; Zn(2+) acts as an agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity); Belongs to the G-protein coupled receptor 1 family.

Synonyms:  GPR39,  GPR39p,  hGPR39,  A0A087WTL7,  O43194 ...

Linkouts:  STRING  Pharos  UniProt  OMIM