DISEASES

Disease-gene associations mined from literature

Literature on SESN3

SESN3 [ENSP00000441927]

Sestrin-3; May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway . May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity). This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity).

Synonyms:  SESN3,  SESN3p,  hSESN3,  A0A0U1RR17,  F5H1K7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM