DISEASES

Disease-gene associations mined from literature

Literature on TLE3

TLE3 [ENSP00000452871]

Transducin-like enhancer protein 3; Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full- length TLE family members may be modulated by association with dominant-negative AES (By similarity).

Synonyms:  TLE3,  TLE3p,  hTLE3,  A0A0D9SES8,  F5H7D6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM