DISEASES

Disease-gene associations mined from literature

Literature on DAO

DAO [ENSP00000228476]

D-amino-acid oxidase; Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids; Belongs to the DAMOX/DASOX family.

Synonyms:  DAO,  A0A024RBI1,  A0A0B4J250,  A0A0B4J257,  F8VV35 ...

Linkouts:  STRING  Pharos  UniProt  OMIM