DISEASES

Disease-gene associations mined from literature

Literature on LBP

LBP [ENSP00000217407]

Lipopolysaccharide-binding protein; Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria . Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:7517398, PubMed:24120359). ECO:0000269|PubMed:20133493, ECO:0000269|PubMed:24120359,

Synonyms:  LBP,  P18428,  P18428p,  hP18428,  3929 ...

Linkouts:  STRING  Pharos  UniProt  OMIM