Literature on CD320
CD320 [ENSP00000301458]
CD320 antigen; Receptor for transcobalamin saturated with cobalamin (TCbl) . Plays an important role in cobalamin uptake . Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells . Functions as costimulator to promote B cell responses to antigenic stimuli; promotes B cell differentiation and proliferation (PubMed:10727470, PubMed:11418631). Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC) . CD320 augments the proliferation of PC precursors generated by IL-10 . ECO:0000269|PubMed:11418631, ECO:0000269|PubMed:18779389,
Synonyms: CD320, CD320p, hCD320, M0R100, M0R1C4 ...