DISEASES

Disease-gene associations mined from literature

Literature on AARS2

AARS2 [ENSP00000244571]

Alanine--tRNA ligase, mitochondrial; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. ; Belongs to the class-II aminoacyl-tRNA synthetase family.

Synonyms:  AARS2,  AARS2p,  hAARS2,  Q5JTZ9,  Q5JTZ9p ...

Linkouts:  STRING  Pharos  UniProt  OMIM