DISEASES

Disease-gene associations mined from literature

Literature on CX3CR1

CX3CR1 [ENSP00000351059]

CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions . Acts as coreceptor with CD4 for HIV- 1 virus envelope protein (in vitro) . Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1 . ECO:0000269|PubMed:23125415, ECO:0000269|PubMed:9390561,

Synonyms:  CX3CR1,  CX3CR1p,  hCX3CR1,  C9JLM2,  C9JN40 ...

Linkouts:  STRING  Pharos  UniProt  OMIM