DISEASES

Disease-gene associations mined from literature

Literature on YWHAE

YWHAE [ENSP00000264335]

14-3-3 protein epsilon; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (By similarity). Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm .

Synonyms:  YWHAE,  B4DJF2,  HEL2,  I3L0W5,  I3L3T1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM