DISEASES

Disease-gene associations mined from literature

Literature on ABCB5

ABCB5 [ENSP00000384881]

ATP-binding cassette sub-family B member 5; Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.

Synonyms:  ABCB5,  ABCB5p,  hABCB5,  A0A024RA03,  H7C165 ...

Linkouts:  STRING  Pharos  UniProt  OMIM