DISEASES

Disease-gene associations mined from literature

Literature on NXN

NXN [ENSP00000337443]

Nucleoredoxin; Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity). ; Belongs to the nucleoredoxin family.

Synonyms:  NXN,  A0A0C4DGI2,  I3L4V6,  Q6DKJ4,  I3L4V6p ...

Linkouts:  STRING  Pharos  UniProt  OMIM