DISEASES

Disease-gene associations mined from literature

Literature on PTGER1

PTGER1 [ENSP00000292513]

Prostaglandin E2 receptor EP1 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues; Belongs to the G-protein coupled receptor 1 family.

Synonyms:  PTGER1,  PTGER1p,  hPTGER1,  P34995,  P34995p ...

Linkouts:  STRING  Pharos  UniProt  OMIM