DISEASES

Disease-gene associations mined from literature

Literature on GUCY2F

GUCY2F [ENSP00000218006]

Retinal guanylyl cyclase 2; Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors . Plays an essential role in phototransduction, by mediating cGMP replenishment (By similarity). May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity). ; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Synonyms:  GUCY2F,  GUCY2Fp,  hGUCY2F,  P51841,  P51841p ...

Linkouts:  STRING  Pharos  UniProt  OMIM