DISEASES

Disease-gene associations mined from literature

Literature on SAT1

SAT1 [ENSP00000368572]

Diamine acetyltransferase 1; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)- acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine; Belongs to the acetyltransferase family.

Synonyms:  SAT1,  SAT1p,  hSAT1,  A0A384NQ10,  A6NJE6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM