DISEASES

Disease-gene associations mined from literature

Literature on CHD1L

CHD1L [ENSP00000358262]

Chromodomain-helicase-DNA-binding protein 1-like; DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP- dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding; Belongs to the SNF2/RAD54 helicase family.

Synonyms:  CHD1L,  CHD1Lp,  hCHD1L,  A0A087WTM4,  A0A087WWW4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM