DISEASES

Disease-gene associations mined from literature

Literature on NME8

NME8 [ENSP00000199447]

Thioredoxin domain-containing protein 3; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds.

Synonyms:  NME8,  NME8p,  hNME8,  C9JG62,  C9JIT0 ...

Linkouts:  STRING  Pharos  UniProt