DISEASES

Disease-gene associations mined from literature

Literature on MTUS1

MTUS1 [ENSP00000262102]

Microtubule-associated tumor suppressor 1; Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.

Synonyms:  MTUS1,  MTUS1p,  hMTUS1,  A0A0U1RQI2,  H0YC63 ...

Linkouts:  STRING  Pharos  UniProt  OMIM