DISEASES

Disease-gene associations mined from literature

Literature on CHSY1

CHSY1 [ENSP00000254190]

Chondroitin sulfate synthase 1; Has both beta-1,3-glucuronic acid and beta-1,4-N- acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.

Synonyms:  CHSY1,  CHSY1p,  hCHSY1,  A0A2R8Y7B7,  Q86X52 ...

Linkouts:  STRING  Pharos  UniProt  OMIM