DISEASES

Disease-gene associations mined from literature

Literature on PTGFRN

PTGFRN [ENSP00000376899]

Prostaglandin F2 receptor negative regulator; Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration (By similarity).

Synonyms:  PTGFRN,  Q9P2B2,  Q9P2B2p,  hQ9P2B2,  5738 ...

Linkouts:  STRING  Pharos  UniProt  OMIM