DISEASES

Disease-gene associations mined from literature

Literature on DRAP1

DRAP1 [ENSP00000307850]

Dr1-associated corepressor; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.

Synonyms:  DRAP1,  DRAP1p,  hDRAP1,  C9JCC6,  E9PMW2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM