DISEASES

Disease-gene associations mined from literature

Literature on NKX2-2

NKX2-2 [ENSP00000366347]

Homeobox protein Nkx-2.2; Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity); Belongs to the NK-2 homeobox family.

Synonyms:  NKX2-2,  O95096,  O95096p,  hO95096,  4821 ...

Linkouts:  STRING  Pharos  UniProt