DISEASES

Disease-gene associations mined from literature

Literature on ADIPOR2

ADIPOR2 [ENSP00000349616]

Adiponectin receptor protein 2; Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism . Required for normal body fat and glucose homeostasis. ADIPOQ-binding activates a signaling cascade that leads to increased PPARA activity, and ultimately to increased fatty acid oxidation and glucose uptake. Has intermediate affinity for globular and full-length adiponectin. Required for normal revascularization after chronic ischemia caused by severing of blood vessels (By similarity); Belongs to the ADIPOR family.

Synonyms:  ADIPOR2,  ADIPOR2p,  hADIPOR2,  Q86V24,  Q86V24p ...

Linkouts:  STRING  Pharos  UniProt  OMIM