DISEASES

Disease-gene associations mined from literature

Literature on B4GALT6

B4GALT6 [ENSP00000306459]

Beta-1,4-galactosyltransferase 6; Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) . LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). ; Belongs to the glycosyltransferase 7 family.

Synonyms:  B4GALT6,  B4GALT6p,  hB4GALT6,  G3XA83,  J3QQY9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM