DISEASES

Disease-gene associations mined from literature

Literature on WDR54

WDR54 [ENSP00000006526]

WD repeat-containing protein 54; When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation.

Synonyms:  WDR54,  WDR54p,  hWDR54,  Q9H977,  Q9H977p ...

Linkouts:  STRING  Pharos  UniProt