DISEASES

Disease-gene associations mined from literature

Literature on SERPIND1

SERPIND1 [ENSP00000215727]

Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan- independent manner; Belongs to the serpin family.

Synonyms:  SERPIND1,  P05546,  P05546p,  hP05546,  1JMJ ...

Linkouts:  STRING  Pharos  UniProt  OMIM