DISEASES

Disease-gene associations mined from literature

Literature on ATG13

ATG13 [ENSP00000432412]

Autophagy-related protein 13; Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. ECO:0000269|PubMed:19225151, ECO:0000269|PubMed:19287211,

Synonyms:  ATG13,  ATG13p,  hATG13,  A0A1B0GXJ3,  E9PPR2 ...

Linkouts:  STRING  Pharos  UniProt  OMIM