DISEASES

Disease-gene associations mined from literature

Literature on FBXO10

FBXO10 [ENSP00000403802]

F-box only protein 10; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The SCF(FBXO10) complex mediates ubiquitination and degradation of BCL2, an antiapoptotic protein, thereby playing a role in apoptosis by controlling the stability of BCL2.

Synonyms:  FBXO10,  FBXO10p,  hFBXO10,  F5GXN9,  J3KN78 ...

Linkouts:  STRING  Pharos  UniProt  OMIM