DISEASES

Disease-gene associations mined from literature

Literature on SLC30A5

SLC30A5 [ENSP00000379836]

Zinc transporter 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP. ECO:0000269|PubMed:11937503, ECO:0000269|PubMed:15276077,

Synonyms:  SLC30A5,  SLC30A5p,  hSLC30A5,  D6REM2,  H0Y957 ...

Linkouts:  STRING  Pharos  UniProt  OMIM