DISEASES

Disease-gene associations mined from literature

Literature on SSC5D

SSC5D [ENSP00000374274]

Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D; Binds to extracellular matrix proteins. Binds to pathogen- associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces (By similarity).

Synonyms:  SSC5D,  SSC5Dp,  hSSC5D,  A1L4H1,  K7EPL3 ...

Linkouts:  STRING  Pharos  UniProt