DISEASES

Disease-gene associations mined from literature

Literature on LCE3A

LCE3A [ENSP00000335006]

Late cornified envelope protein 3A; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens ; Belongs to the LCE family.

Synonyms:  LCE3A,  LCE3Ap,  hLCE3A,  Q5TA76,  Q5TA76p ...

Linkouts:  STRING  Pharos  UniProt  OMIM